It all starts with the excision of a small human cortical piece
My research integrates advanced neurophysiological and microscopic techniques, with histology and cutting-edge signal processing analysis to explore the fundamental aspects of brain function under health and disease. I focus on cellular communication and network dynamics and interrogate the interplay between intrinsic ionic mechanisms, synaptic transmission and native glial dynamics in relation to physiological and pathophysiological states in neurodegenerative disorders such as multiple sclerosis, Parkinson’s and Alzheimer’s Disease.
Single cell functional investigations using Human neurosurgical samples
Neuromorphological reconstructions in human cortical slices
Electrical properties of excitatory and inhibitory cells in human cortex
Computational Modelling (Cellular and Network)
Multielectrode Network Electrophysiology
Human EEG Analysis
Deep Learning and Class Prediction Analysis
